Nh\u1eefng r\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p trong khi ng\u1ee7 c\u00f3 th\u1ec3 \u0111\u00f3ng m\u1ed9t vai tr\u00f2 b\u1ea5t ng\u1edd trong s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a b\u1ec7nh Alzheimer. H\u1ed9i ch\u1ee9ng ng\u01b0ng th\u1edf khi ng\u1ee7 do t\u1eafc ngh\u1ebdn, m\u1ed9t r\u1ed1i lo\u1ea1n ph\u1ed5 bi\u1ebfn \u0111\u1eb7c tr\u01b0ng b\u1edfi nh\u1eefng l\u1ea7n ng\u1eebng th\u1edf l\u1eb7p \u0111i l\u1eb7p l\u1ea1i v\u00e0o ban \u0111\u00eam, khi\u1ebfn n\u00e3o b\u1ed9 ph\u1ea3i ch\u1ecbu nh\u1eefng chu k\u1ef3 thi\u1ebfu oxy sau \u0111\u00f3 l\u00e0 t\u00e1i oxy h\u00f3a. Nh\u1eefng bi\u1ebfn \u0111\u1ed9ng n\u00e0y, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 thi\u1ebfu oxy gi\u00e1n \u0111o\u1ea1n, kh\u00f4ng ph\u1ea3i kh\u00f4ng g\u00e2y h\u1eadu qu\u1ea3 cho c\u00e1c t\u1ebf b\u00e0o n\u00e3o, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ebf b\u00e0o h\u00ecnh sao. Nh\u1eefng t\u1ebf b\u00e0o n\u00e0y, t\u1eeb l\u00e2u \u0111\u01b0\u1ee3c coi l\u00e0 ch\u1ec9 h\u1ed7 tr\u1ee3 c\u00e1c n\u01a1-ron, th\u1ef1c t\u1ebf l\u1ea1i ho\u1ea1t \u0111\u1ed9ng nh\u01b0 nh\u1eefng c\u1ea3m bi\u1ebfn oxy v\u00e0 \u0111i\u1ec1u ch\u1ec9nh vi\u00eam, l\u01b0u l\u01b0\u1ee3ng m\u00e1u v\u00e0 lo\u1ea1i b\u1ecf ch\u1ea5t th\u1ea3i \u0111\u1ed9c h\u1ea1i trong n\u00e3o.<\/p>\n
Khi m\u1ed9t ng\u01b0\u1eddi m\u1eafc h\u1ed9i ch\u1ee9ng ng\u01b0ng th\u1edf khi ng\u1ee7, c\u00e1c t\u1ebf b\u00e0o h\u00ecnh sao c\u1ee7a h\u1ecd ph\u1ea3i ch\u1ecbu c\u0103ng th\u1eb3ng l\u1eb7p \u0111i l\u1eb7p l\u1ea1i. Th\u00f4ng th\u01b0\u1eddng c\u00f3 t\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7, ch\u00fang tr\u1edf th\u00e0nh ngu\u1ed3n g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng: ch\u00fang s\u1ea3n sinh nhi\u1ec1u ph\u00e2n t\u1eed g\u00e2y vi\u00eam v\u00e0 c\u00e1c g\u1ed1c t\u1ef1 do h\u01a1n, nh\u1eefng ch\u1ea5t g\u00e2y h\u1ea1i cho c\u00e1c n\u01a1-ron. Tuy nhi\u00ean, nh\u1eefng c\u01a1 ch\u1ebf n\u00e0y c\u0169ng li\u00ean quan \u0111\u1ebfn b\u1ec7nh Alzheimer, n\u01a1i ng\u01b0\u1eddi ta quan s\u00e1t th\u1ea5y s\u1ef1 t\u00edch t\u1ee5 b\u1ea5t th\u01b0\u1eddng c\u1ee7a c\u00e1c protein \u0111\u1ed9c h\u1ea1i nh\u01b0 beta-amyloid v\u00e0 s\u1ef1 tho\u00e1i h\u00f3a d\u1ea7n d\u1ea7n c\u1ee7a c\u00e1c t\u1ebf b\u00e0o n\u00e3o. C\u00e1c t\u1ebf b\u00e0o h\u00ecnh sao, khi m\u1ea5t \u0111i ch\u1ee9c n\u0103ng b\u1ea3o v\u1ec7, c\u00f3 th\u1ec3 do \u0111\u00f3 th\u00fac \u0111\u1ea9y s\u1ef1 xu\u1ea5t hi\u1ec7n v\u00e0 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam c\u00e1c t\u1ed5n th\u01b0\u01a1ng \u0111i\u1ec3n h\u00ecnh c\u1ee7a b\u1ec7nh.<\/p>\n
C\u00e1c nghi\u00ean c\u1ee9u d\u1ecbch t\u1ec5 h\u1ecdc x\u00e1c nh\u1eadn m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa ng\u01b0ng th\u1edf khi ng\u1ee7 v\u00e0 suy gi\u1ea3m nh\u1eadn th\u1ee9c. Nh\u1eefng ng\u01b0\u1eddi m\u1eafc ng\u01b0ng th\u1edf nghi\u00eam tr\u1ecdng c\u00f3 nguy c\u01a1 cao h\u01a1n ph\u00e1t tri\u1ec3n ch\u1ee9ng m\u1ea5t tr\u00ed nh\u1edb, bao g\u1ed3m c\u1ea3 b\u1ec7nh Alzheimer. Nguy c\u01a1 n\u00e0y d\u01b0\u1eddng nh\u01b0 c\u00f2n r\u00f5 r\u1ec7t h\u01a1n \u1edf ph\u1ee5 n\u1eef sau m\u00e3n kinh, c\u00f3 l\u1ebd do nh\u1eefng thay \u0111\u1ed5i n\u1ed9i ti\u1ebft v\u00e0 chuy\u1ec3n h\u00f3a. Ng\u01b0\u1ee3c l\u1ea1i, nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh Alzheimer th\u01b0\u1eddng xuy\u00ean g\u1eb7p c\u00e1c r\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p v\u1ec1 \u0111\u00eam, g\u1ee3i \u00fd m\u1ed9t m\u1ed1i quan h\u1ec7 hai chi\u1ec1u gi\u1eefa hai t\u00ecnh tr\u1ea1ng n\u00e0y.<\/p>\n
Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb ng\u01b0ng th\u1edf b\u1eb1ng \u00e1p l\u1ef1c d\u01b0\u01a1ng li\u00ean t\u1ee5c, gi\u00fap gi\u1eef cho \u0111\u01b0\u1eddng th\u1edf m\u1edf trong khi ng\u1ee7, c\u00f3 th\u1ec3 mang l\u1ea1i m\u1ed9t h\u01b0\u1edbng \u0111i \u0111\u1ec3 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh suy gi\u1ea3m nh\u1eadn th\u1ee9c. B\u1eb1ng c\u00e1ch c\u1ea3i thi\u1ec7n vi\u1ec7c cung c\u1ea5p oxy cho n\u00e3o, ph\u01b0\u01a1ng ph\u00e1p n\u00e0y gi\u1ea3m c\u0103ng th\u1eb3ng oxy h\u00f3a v\u00e0 ph\u1ee5c h\u1ed3i m\u1ed9t ph\u1ea7n chuy\u1ec3n h\u00f3a n\u00e3o. M\u1eb7c d\u00f9 k\u1ebft qu\u1ea3 v\u1eabn c\u00f2n s\u01a1 b\u1ed9, ch\u00fang m\u1edf ra con \u0111\u01b0\u1eddng cho vi\u1ec7c qu\u1ea3n l\u00fd t\u1ed1t h\u01a1n c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 c\u00f3 th\u1ec3 thay \u0111\u1ed5i c\u1ee7a ch\u1ee9ng m\u1ea5t tr\u00ed nh\u1edb.<\/p>\n
Nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y nh\u1ea5n m\u1ea1nh t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c s\u00e0ng l\u1ecdc v\u00e0 \u0111i\u1ec1u tr\u1ecb ng\u01b0ng th\u1edf khi ng\u1ee7, kh\u00f4ng ch\u1ec9 \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng gi\u1ea5c ng\u1ee7, m\u00e0 c\u00f2n \u0111\u1ec3 b\u1ea3o v\u1ec7 n\u00e3o b\u1ed9 trong d\u00e0i h\u1ea1n. Ch\u00fang c\u0169ng khuy\u1ebfn kh\u00edch kh\u00e1m ph\u00e1 c\u00e1c chi\u1ebfn l\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb m\u1edbi nh\u1eafm c\u1ee5 th\u1ec3 v\u00e0o r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng c\u1ee7a t\u1ebf b\u00e0o h\u00ecnh sao, nh\u1eb1m ph\u00e1 v\u1ee1 v\u00f2ng lu\u1ea9n qu\u1ea9n gi\u1eefa thi\u1ebfu oxy, vi\u00eam v\u00e0 tho\u00e1i h\u00f3a th\u1ea7n kinh.<\/p>\n
DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1007\/s11325-026-03651-w<\/a><\/p>\n Titre\u00a0:<\/strong> Astrocytes at the crossroads of obstructive sleep apnea and Alzheimer\u2019s disease: from oxygen sensing to neurodegeneration<\/p>\n Revue : <\/strong> Sleep and Breathing<\/p>\n \u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n Auteurs : <\/strong> J. Cabot; J. B. Soriano; A. Alonso-Fern\u00e1ndez; J. J. Rodr\u00edguez; J. J. Merino; L. C\u00e0naves-G\u00f3mez; N. Gay\u00e0-Caro; X. Busquets<\/p>\n","protected":false},"excerpt":{"rendered":" Thi\u1ebfu oxy trong khi ng\u1ee7 c\u00f3 l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 b\u1ec7nh Alzheimer kh\u00f4ng? Nh\u1eefng r\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p trong khi ng\u1ee7 c\u00f3 th\u1ec3 \u0111\u00f3ng m\u1ed9t vai tr\u00f2 b\u1ea5t ng\u1edd trong s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a b\u1ec7nh Alzheimer. H\u1ed9i ch\u1ee9ng ng\u01b0ng th\u1edf khi ng\u1ee7 do t\u1eafc ngh\u1ebdn, m\u1ed9t r\u1ed1i lo\u1ea1n ph\u1ed5 bi\u1ebfn \u0111\u1eb7c tr\u01b0ng b\u1edfi nh\u1eefng l\u1ea7n… Continue reading Thi\u1ebfu oxy trong khi ng\u1ee7 c\u00f3 l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 b\u1ec7nh Alzheimer kh\u00f4ng?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,2],"tags":[],"class_list":["post-19","post","type-post","status-publish","format-standard","hentry","category-nhan-dao-con-nguoi","category-suc-khoe","entry"],"_links":{"self":[{"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/posts\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/comments?post=19"}],"version-history":[{"count":1,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/posts\/19\/revisions"}],"predecessor-version":[{"id":20,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/posts\/19\/revisions\/20"}],"wp:attachment":[{"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/media?parent=19"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/categories?post=19"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/themedicaltribune.com\/vi\/wp-json\/wp\/v2\/tags?post=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}