{"id":31,"date":"2026-06-13T11:04:59","date_gmt":"2026-06-13T09:04:59","guid":{"rendered":"https:\/\/themedicaltribune.com\/zh-tw\/2026\/06\/13\/crispr-%e5%b7%a5%e5%85%b7%e7%82%ba%e5%91%bc%e5%90%b8%e9%81%93%e7%97%85%e6%af%92%e6%84%9f%e6%9f%93%e6%8f%90%e4%be%9b%e6%96%b0%e6%ad%a6%e5%99%a8\/"},"modified":"2026-06-13T11:05:59","modified_gmt":"2026-06-13T09:05:59","slug":"crispr-%e5%b7%a5%e5%85%b7%e7%82%ba%e5%91%bc%e5%90%b8%e9%81%93%e7%97%85%e6%af%92%e6%84%9f%e6%9f%93%e6%8f%90%e4%be%9b%e6%96%b0%e6%ad%a6%e5%99%a8","status":"publish","type":"post","link":"https:\/\/themedicaltribune.com\/zh-tw\/2026\/06\/13\/crispr-%e5%b7%a5%e5%85%b7%e7%82%ba%e5%91%bc%e5%90%b8%e9%81%93%e7%97%85%e6%af%92%e6%84%9f%e6%9f%93%e6%8f%90%e4%be%9b%e6%96%b0%e6%ad%a6%e5%99%a8\/","title":{"rendered":"CRISPR \u5de5\u5177\u70ba\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u63d0\u4f9b\u65b0\u6b66\u5668"},"content":{"rendered":"

CRISPR \u5de5\u5177\u70ba\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u63d0\u4f9b\u65b0\u6b66\u5668<\/h1>\n

\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u662f\u5168\u7403\u5065\u5eb7\u9762\u81e8\u7684\u91cd\u5927\u6311\u6230\uff0c\u6bcf\u5e74\u6709\u6578\u5341\u842c\u4eba\u56e0\u6d41\u611f\u3001\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u6216SARS-CoV-2\u7b49\u75c5\u6bd2\u6b7b\u4ea1\u3002\u96d6\u7136\u75ab\u82d7\u548c\u6297\u75c5\u6bd2\u85e5\u7269\u767c\u63ee\u8457\u95dc\u9375\u4f5c\u7528\uff0c\u4f46\u5176\u6709\u6548\u6027\u53ef\u80fd\u53d7\u5230\u75c5\u6bd2\u5feb\u901f\u6f14\u8b8a\u548c\u8010\u85e5\u6027\u51fa\u73fe\u7684\u9650\u5236\u3002\u4e00\u7a2e\u57fa\u65bcCRISPR\u6280\u8853\u7684\u5275\u65b0\u65b9\u6cd5\uff0c\u80fd\u5920\u76f4\u63a5\u91dd\u5c0d\u75c5\u6bd2\u7684\u907a\u50b3\u7269\u8cea\u6216\u5176\u8907\u88fd\u6240\u9700\u7684\u7d30\u80de\u56e0\u5b50\u3002<\/p>\n

\u9019\u7a2e\u65b9\u6cd5\u4f7f\u7528\u53ef\u7de8\u7a0b\u9176\uff0c\u5982\u91dd\u5c0dRNA\u75c5\u6bd2\u7684Cas13\u6216\u91dd\u5c0dDNA\u75c5\u6bd2\u7684Cas9\u548cCas12\uff0c\u80fd\u5920\u5207\u5272\u7279\u5b9a\u7684\u75c5\u6bd2\u5e8f\u5217\u3002\u5728\u5be6\u9a57\u5ba4\u4e2d\uff0c\u5c0d\u4eba\u985e\u80ba\u7d30\u80de\u57f9\u990a\u7269\u548c\u52d5\u7269\u6a21\u578b\u7684\u7814\u7a76\u8868\u660e\uff0c\u9019\u4e9b\u5de5\u5177\u80fd\u5920\u964d\u4f4e\u6d41\u611f\u6216SARS-CoV-2\u7684\u75c5\u6bd2\u8f09\u91cf\u3002\u4f8b\u5982\uff0c\u5c07Cas13a\u4ee5\u4fe1\u4f7fRNA\u7684\u5f62\u5f0f\u6ce8\u5c04\u5230\u5c0f\u9f20\u6216\u5009\u9f20\u7684\u80ba\u90e8\uff0c\u901a\u904e\u9f3b\u8154\u6216\u6c23\u9727\u9014\u5f91\u7d66\u85e5\u5f8c\uff0c\u80fd\u986f\u8457\u6e1b\u5c11\u75c5\u6bd2\u6578\u91cf\u3002<\/p>\n

\u9019\u9805\u6280\u8853\u7684\u4e00\u500b\u4e3b\u8981\u512a\u52e2\u5728\u65bc\u5176\u5feb\u901f\u9069\u61c9\u80fd\u529b\u3002\u901a\u904e\u91dd\u5c0d\u75c5\u6bd2\u57fa\u56e0\u7d44\u4e2d\u4fdd\u5b88\u7684\u5340\u57df\uff08\u5373\u4e0d\u6613\u767c\u751f\u7a81\u8b8a\u7684\u5340\u57df\uff09\uff0c\u7814\u7a76\u4eba\u54e1\u964d\u4f4e\u4e86\u75c5\u6bd2\u9003\u9038\u7684\u98a8\u96aa\u3002\u6b64\u5916\uff0c\u540c\u6642\u4f7f\u7528\u591a\u500bRNA\u5c0e\u5411\u5e8f\u5217\u53ef\u4ee5\u91dd\u5c0d\u57fa\u56e0\u7d44\u7684\u591a\u500b\u90e8\u5206\uff0c\u9019\u4f7f\u5f97\u75c5\u6bd2\u66f4\u96e3\u7522\u751f\u8010\u85e5\u6027\u3002\u9019\u7a2e\u7a31\u70ba\u591a\u91cd\u5316\u7684\u7b56\u7565\u5df2\u7d93\u5728\u5c0d\u6297SARS-CoV-2\u7684\u591a\u7a2e\u8b8a\u7570\u682a\u4e2d\u8b49\u660e\u4e86\u5176\u6709\u6548\u6027\uff0c\u4e26\u53ef\u80fd\u64f4\u5c55\u5230\u5176\u4ed6\u547c\u5438\u9053\u75c5\u6bd2\u3002<\/p>\n

\u7136\u800c\uff0c\u76f4\u63a5\u5c07CRISPR\u5de5\u5177\u8f38\u9001\u5230\u80ba\u90e8\u4ecd\u9762\u81e8\u6311\u6230\u3002\u75c5\u6bd2\u8f09\u9ad4\uff08\u5982\u817a\u75c5\u6bd2\uff09\u80fd\u5be6\u73fe\u9176\u7684\u6301\u4e45\u8868\u9054\uff0c\u4f46\u53ef\u80fd\u5f15\u767c\u514d\u75ab\u53cd\u61c9\u6216\u5728\u904b\u8f38\u907a\u50b3\u7269\u8cea\u65b9\u9762\u5b58\u5728\u5c3a\u5bf8\u9650\u5236\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u8102\u8cea\u7d0d\u7c73\u9846\u7c92\u63d0\u4f9b\u4e86\u66f4\u9748\u6d3b\u7684\u89e3\u6c7a\u65b9\u6848\u3002\u5b83\u5011\u80fd\u5be6\u73fe\u66ab\u6642\u6027\u8868\u9054\uff0c\u9069\u5408\u6025\u6027\u611f\u67d3\uff0c\u4e26\u53ef\u901a\u904e\u6c23\u9727\u65b9\u5f0f\u7d66\u85e5\u3002\u6700\u8fd1\u7684\u7814\u7a76\u5df2\u8b49\u660e\u5176\u80fd\u6709\u6548\u5730\u5c07\u7de8\u78bcCas13\u7684\u4fe1\u4f7fRNA\u8f38\u9001\u5230\u5c0f\u9f20\u80ba\u90e8\uff0c\u5177\u6709\u826f\u597d\u7684\u8010\u53d7\u6027\u4e26\u986f\u8457\u964d\u4f4e\u75c5\u6bd2\u8f09\u91cf\u3002<\/p>\n

CRISPR\u7684\u53e6\u4e00\u500b\u512a\u52e2\u5728\u65bc\u5176\u8abf\u63a7\u75c5\u6bd2\u611f\u67d3\u76f8\u95dc\u7d30\u80de\u56e0\u5b50\u7684\u80fd\u529b\u3002\u4f8b\u5982\uff0c\u901a\u904e\u963b\u65b7\u80f1\u6eb6\u7d20L\u7684\u8868\u9054\uff08\u9019\u662fSARS-CoV-2\u9032\u5165\u7d30\u80de\u6240\u9700\u7684\u9176\uff09\uff0c\u53ef\u4ee5\u5728\u4e0d\u76f4\u63a5\u91dd\u5c0d\u75c5\u6bd2\u7684\u60c5\u6cc1\u4e0b\u6e1b\u5c11\u611f\u67d3\u3002\u9019\u7a2e\u65b9\u6cd5\u7684\u512a\u9ede\u5728\u65bc\u80fd\u964d\u4f4e\u8010\u85e5\u6027\u98a8\u96aa\uff0c\u56e0\u70ba\u5b83\u91dd\u5c0d\u7684\u662f\u4fdd\u5b88\u7684\u7d30\u80de\u6a5f\u5236\uff0c\u800c\u975e\u4e0d\u65b7\u8b8a\u5316\u7684\u75c5\u6bd2\u5e8f\u5217\u3002<\/p>\n

\u5269\u9918\u7684\u6311\u6230\u5305\u62ec\u512a\u5316\u8f38\u9001\u65b9\u5f0f\uff0c\u4ee5\u907f\u514d\u7d0d\u7c73\u9846\u7c92\u88ab\u9ecf\u6db2\u6216\u80ba\u90e8\u9632\u79a6\u6a5f\u5236\u6355\u7372\uff0c\u4ee5\u53ca\u6700\u5c0f\u5316\u526f\u4f5c\u7528\uff0c\u5982\u91dd\u5c0dCRISPR\u9176\u6216\u8f38\u9001\u8f09\u9ad4\u7684\u514d\u75ab\u53cd\u61c9\u3002\u885b\u751f\u76e3\u7ba1\u6a5f\u69cb\u9084\u8981\u6c42\u5728\u81e8\u5e8a\u61c9\u7528\u524d\u63d0\u4f9b\u95dc\u65bc\u7642\u6cd5\u5728\u9ad4\u5167\u5206\u4f48\u3001\u6301\u4e45\u6027\u548c\u9577\u671f\u5b89\u5168\u6027\u7684\u53ef\u9760\u6578\u64da\u3002<\/p>\n

\u672a\u4f86\uff0c\u5c07CRISPR\u6280\u8853\u8207\u5feb\u901f\u6e2c\u5e8f\u65b9\u6cd5\u76f8\u7d50\u5408\uff0c\u53ef\u80fd\u5be6\u73fe\u5be6\u6642\u500b\u6027\u5316\u7642\u6cd5\u3002\u901a\u904e\u5206\u6790\u60a3\u8005\u9ad4\u5167\u75c5\u6bd2\u7684\u57fa\u56e0\u7d44\uff0c\u53ef\u4ee5\u8a2d\u8a08\u5b9a\u5236\u7684RNA\u5c0e\u5411\u5e8f\u5217\uff0c\u7cbe\u78ba\u91dd\u5c0d\u611f\u67d3\u7684\u75c5\u6bd2\u682a\u3002\u6b64\u5916\uff0c\u9810\u5148\u8a2d\u8a08\u7684\u5c0e\u5411\u5e8f\u5217\u5eab\u53ef\u4ee5\u5132\u5b58\u4e26\u5feb\u901f\u90e8\u7f72\uff0c\u4ee5\u61c9\u5c0d\u75ab\u60c5\u7206\u767c\uff0c\u70ba\u65b0\u8208\u75c5\u6bd2\u63d0\u4f9b\u5373\u6642\u61c9\u5c0d\u3002<\/p>\n

\u6700\u5f8c\uff0cCRISPR\u53ef\u4ee5\u8207\u5176\u4ed6\u65b9\u6cd5\uff08\u5982\u6297\u5fae\u751f\u7269\u80bd\u6216\u6297\u9ad4\uff09\u7d50\u5408\uff0c\u4ee5\u589e\u5f37\u6cbb\u7642\u6548\u679c\u3002\u9019\u7a2e\u7d50\u5408\u4e0d\u50c5\u80fd\u6cbb\u7642\u75c5\u6bd2\u611f\u67d3\uff0c\u9084\u80fd\u6e1b\u5c11\u6297\u751f\u7d20\u7684\u4f7f\u7528\uff0c\u5f9e\u800c\u9650\u5236\u7d30\u83cc\u8010\u85e5\u6027\u7684\u51fa\u73fe\u3002\u96a8\u8457\u8f38\u9001\u3001\u5b89\u5168\u6027\u548c\u76e3\u7ba1\u65b9\u9762\u7684\u6301\u7e8c\u9032\u5c55\uff0c\u57fa\u65bcCRISPR\u7684\u7642\u6cd5\u53ef\u80fd\u4e0d\u4e45\u5c07\u6210\u70ba\u5c0d\u6297\u547c\u5438\u9053\u611f\u67d3\u7684\u91cd\u8981\u6b66\u5668\u3002<\/p>\n

\n

Sources utilis\u00e9es<\/h2>\n

Source du rapport<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1007\/s44370-026-00045-0<\/a><\/p>\n

Titre\u00a0:<\/strong> CRISPR-based therapeutics to combat respiratory viral infections<\/p>\n

Revue : <\/strong> Discover Viruses<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Piyush Baindara; Roy Dinata<\/p>\n","protected":false},"excerpt":{"rendered":"

CRISPR \u5de5\u5177\u70ba\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u63d0\u4f9b\u65b0\u6b66\u5668 \u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u662f\u5168\u7403\u5065\u5eb7\u9762\u81e8\u7684\u91cd\u5927\u6311\u6230\uff0c\u6bcf\u5e74\u6709\u6578\u5341\u842c\u4eba\u56e0\u6d41\u611f\u3001\u547c… \u95b1\u8b80\u5168\u6587 CRISPR \u5de5\u5177\u70ba\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u63d0\u4f9b\u65b0\u6b66\u5668<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,5],"tags":[],"class_list":["post-31","post","type-post","status-publish","format-standard","hentry","category-2","category-5","entry"],"_links":{"self":[{"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/posts\/31","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/comments?post=31"}],"version-history":[{"count":1,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/posts\/31\/revisions"}],"predecessor-version":[{"id":32,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/posts\/31\/revisions\/32"}],"wp:attachment":[{"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/media?parent=31"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/categories?post=31"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/themedicaltribune.com\/zh-tw\/wp-json\/wp\/v2\/tags?post=31"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}